Card image cap
Ultrafast Raman spectroscopy

K. Hiramatsu, T. Tajima, and K. Goda, "Ultrafast, dual-band coherent Raman spectroscopy without ultrashort pulses", ACS Photonics (2022)



flag flag flag

Card image cap
Wearable/Flexible SERS

L. Liu, S. Noguchi, T. Xiao, S. Karhadkar, K. Hiramatsu, H. Segawa, T. Itoh, J. Qu, K. Takei, and K. Goda, "Highly scalable, wearable surface-enhanced Raman spectroscopy", Advanced Optical Materials (2022)

flag flag flag

Card image cap
3D particle manipulation

Y. Shen, Y. Yuan, T. Tang, N. Ota, N. Tanaka, Y. Hosokawa, Y. Yalikun, and Y. Tanaka, "Continuous 3D particles manipulation based on cooling thermal convection", Sensors and Actuators B: Chemical (2022)

flag

Card image cap
Cell component tracking

T. Tang, X. Liu, Y. Yuan, .., M. Li, Y. Hosokawa, and Y. Yalikun, "Impedance-based tracking of the loss of intracellular components in microalgae cells", Sensors and Actuators B: Chemical (2022)

flag flag

Card image cap
Broadband impulsive Raman

W. Peterson, J. Gala de Pablo, M. Lindley, K. Hiramatsu, and K. Goda, "Ultrafast impulsive Raman spectroscopy across the THz-fingerprint region", Advanced Photonics (2022)

flag flag flag

Card image cap
Gas velocity sensor

Y. Hao, Y. Tanaka, Y. Hosokawa, M. Li, and Y. Yalikun, "A gas flow velocity sensor fabricated with femtosecond laser using 4 μm ultra-thin glass sheet", Applied Physics Express (2022)

flag flag

Card image cap
Microfluidic cell cultivation

D. Anggraini, N. Ota, Y. Shen, T. Tang, Y. Tanaka, Y. Hosokawa, M. Li, and Y. Yalikun, "Recent advances in microfluidic devices for single-cell cultivation: methods and applications", Lab on a Chip (2022)

flag flag

Card image cap
Mitochondrial relocation sorting

J. Harmon, J. Findinier, N. T. Ishii, M. Herbig, A. Isozaki, A. Grossman, and K. Goda, "Intelligent image-activated cell sorting by mitochondrial relocation", Cytometry Part A (2022)


flag flag flag

Card image cap
Fingerprint cell sorting

M. Lindley, J. Gala de Pablo, W. Peterson, A. Isozaki, K. Hiramatsu, K. Goda, "High-throughput Raman-activated cell sorting in the fingerprint region", Advanced Materials Technologies (2022)

flag flag flag

Card image cap
Stenosis imaging

Y. Deng, J. A. Duque, .., M. Nishikawa, T. Xiao, Y. Yatomi, H. W. Hou, and K. Goda, "Understanding stenosis-induced platelet aggregation on a chip by high-speed optical imaging", Sensors and Actuators B: Chemical (2022)

flag flag flag flag

Card image cap
Cell membrane analysis

T. Tang, X. Liu, Y. Yuan, .., M. Li, Y. Hosokawa, and Y. Yalikun, "Assessment of the electrical penetration of cell membranes using four-frequency impedance cytometry", Microsystems & Nanoengineering (2022)

flag

Card image cap
Impedance cytometry of yeast

X. Liu, T. Tang, P. Yi, Y. Yuan, C. Lei, M. Li, Y. Tanaka, Y. Hosokawa, and Y. Yalikun,"Identification of single yeast budding using impedance cytometry with a narrow electrode span", Sensors (2022)

flag flag

Card image cap
Throughput practices

M. Herbig, A. Isozaki, D. Di Carlo, J. Guck, N. Nitta, H. Shintaku, A. Wu, I. Nikaido, .., R. Damoiseaux, and K. Goda, "Best practices for reporting throughput in biomedical research", Nature Methods (2022)

flag flag flag flag

Card image cap
Parallel impedance cytometry

T. Tang, X. Liu, Y. Yuan, .., Y. Tanaka, M. Li, Y. Hosokawa, and Y. Yalikun, "Parallel impedance cytometry for real-time screening of bacterial single cells from nano- to microscale", ACS Sensors (2022)

flag flag

Card image cap
Sort-timing prediction

Y. Zhao, A. Isozaki, M. Herbig, M. Hayashi, K. Hiramatsu, .., S. Ohnuki, Y. Ohya, N. Nitta, and K. Goda, "Intelligent sort-timing prediction for image-activated cell sorting", Cytometry Part A (2022)

flag flag flag

Card image cap
Sorting of imMKCLs

A. Dian, W. Mubarok, .., S. Suetsugu, and Y. Yalikun, "Reverse sorting of immortalized megakaryocyte progenitor cell lines (imMKCLs) by femtosecond laser scanning", Applied Physics Express (2022)

flag

Card image cap
COVID-19 vaccination effect

Y. Zhou, M. Nishikawa, H. Kanno, R. Yang, .., Y. Kanthi, G. K. Rohde, K. Moriya, Y. Yatomi, and K. Goda, "Long-term effects of Pfizer-BioNTech COVID-19 vaccinations on platelets", Cytometry Part A (2022)

flag flag flag

Card image cap
Shape-based separation

T. Zhang, H. Liu, .., Y. Tanaka, D. W Inglis, Y. Hosokawa, Y. Yalikun, and M. Li, "Shape-based separation of drug-treated Escherichia coli using viscoelastic microfluidics", Lab on a Chip (2022)

flag flag

Card image cap
Review of metal-free SERS

P. M. Pancorbo, H. Zhang, X. Yu, T. Xiao, and K. Goda, "Metal-free SERS: where we are now, where we are heading", Europhysics Letters (2022)



flag flag flag

Card image cap
AI-based impedance screening

T. Tang, X. Liu, .., and Y. Yalikun, "Machine learning-based impedance system for real-time recognition of antibiotic-susceptible bacteria with parallel cytometry", Sensors and Actuators B: Chemical (2022)

flag

Card image cap
Deep imaging flow cytometry

K. Huang, H. Matsumura, .., J. Harmon, J. Findinier, M. Yamagishi, S. Ohnuki, N. Nitta, A. Grossman, Y. Ohya, H. Mikami, A. Isozaki, and K. Goda, "Deep imaging flow cytometry", Lab on a Chip (2022)

flag flag flag

Card image cap
Review of ultrafast imaging

D. Wang, S. Wei, X. Yuan, Z. Liu, Y. Weng, Y. Zhou, T. Xiao, K. Goda, S. Liu, and C. Lei, "Ultrafast imaging for uncovering laser-material interaction dynamics", International Journal of Mechanical System Dynamics (2022)

flag flag flag

Card image cap
COVID-19-associated thrombosis

M. Nishikawa, H. Kanno, Y. Zhou, .., Y. Yatomi, and K. Goda, "Massive image-based single-cell profiling reveals high levels of circulating platelet aggregates in patients with COVID-19", Nature Communications (2021)

flag flag flag

Card image cap
Lactate indicator

R. Bekdash, J. R. Quejada, S. Ueno, F. Kawano, K. Morikawa, .., S. O. Marx, K. Goda, and M. Yazawa, "GEM-IL: a highly responsive fluorescent lactate indicator", Cell Reports Methods (2021)

flag flag flag

Card image cap
Sepsis therapy

H. Koide,.., T. Xiao, K. Goda, N. Oku, T. Asai, and K. J. Shea, "Synthetic hydrogel nanoparticles for sepsis therapy", Nature Communications (2021)


flag flag flag

Card image cap
Dielectrophoretic array sorting

M. H. Loo, Y. Nakagawa, A. Isozaki, and K. Goda, "High-throughput sorting of nanoliter droplets enabled by a sequentially addressable dielectrophoretic array", Electrophoresis (2021)

flag flag flag

Card image cap
Sensitive FT-CARS

M. Lindley, .., K. Hiramatsu, and K. Goda, "Highly sensitive Fourier-transform coherent anti-Stokes Raman scattering spectroscopy via genetic algorithm pulse shaping", Optics Letters (2021)

flag flag flag

Card image cap
Reassessing microdroplets

Y. Nakagawa, S. Ohnuki, N. Kondo, .., A. Isozaki, Y. Ohya, and K. Goda, "Are droplets really suitable for single-cell analysis? A case study on yeast in droplets", Lab on a Chip (2021)


flag flag flag

Card image cap
Low-frequency Raman

P. C. McCann, K. Hiramatsu, and K. Goda, "Highly sensitive low-frequency time-domain Raman spectroscopy via fluorescence-encoding", Journal of Physical Chemistry Letters (2021)


flag flag flag

Card image cap
Multiplexed droplet sorting

A. Isozaki, D. Huang, Y. Nakagawa, and K. Goda, "Dual sequentially addressable dielectrophoretic array for high-throughput, scalable, multiplexed droplet sorting", Microfluidics and Nanofluidics (2021)

flag flag flag

Card image cap
Ca2+ channel control

P. Cheng, X. Tian, W. Tang, J. Cheng, J. Bao, .., K. Goda, and H. He, "Direct control of store-operated calcium channels by ultrafast laser", Cell Research (2021)


flag flag flag

Card image cap
Review of droplet flow cytometry

M. Li, H. Liu, S. Zhuang, and K. Goda, "Droplet flow cytometry for single-cell analysis", RSC Advances (2021)




flag flag flag flag

Card image cap
Review of glass microfluidics

T. Tang, Y. Yuan, .., M. Li, and Y. Tanaka, "Glass-based micro total analysis systems: materials, fabrication methods, and applications", Sensors and Actuators B: Chemical (2021)


flag flag

Card image cap
Sensitive Raman optical activity

T. Xiao, Z. Cheng, Z. Luo, A. Isozaki, K. Hiramatsu, T. Itoh, M. Nomura, S. Iwamoto, and K. Goda, "All-dielectric chiral-field-enhanced Raman optical activity", Nature Communications (2021)

flag flag flag

Card image cap
Intelligent cell indicator

M. Xu, D. Yuan, S. Yan, C. Lei, .., K. Goda, "Morphological indicator of Euglena gracilis with a high heavy metal removal efficiency", Environmental Science and Technology (2021)

flag flag flag

Card image cap
Deep biophysical cytometry

K. C. M. Lee, J. Guck, K. Goda, and K. K. Tsia, "Deep biophysical cytometry: prospects and challenges", Trends in Biotechnology (2021)



flag flag flag flag

Card image cap
Review of Raman flow cytometry

J. Gala de Pablo, M. Lindley, K. Hiramatsu, and K. Goda, "High-throughput Raman flow cytometry and beyond", Accounts of Chemical Research (2021)


flag flag flag

Card image cap
Intelligent platelet morphometry

Y. Zhou, A. Isozaki, A. Yasumoto, T. Xiao, Y. Yatomi, C. Lei, and K. Goda, "Intelligent platelet morphometry", Trends in Biotechnology (2021)



flag flag flag

Card image cap
Ultrathin glass microfluidics

Y. Yuan, Y. Yalikun, .., Y. Shen, and Y. Tanaka, "Fabrication of ultra-thin glass sheet by weight-controlled load-assisted precise thermal stretching", Sensors and Actuators A: Physical (2021)

flag

Card image cap
Cell control by light

P. Cheng, X. Tian, W. Tang, J. Cheng, J. Bao, H. Wang, .., T. Chen, H. Feng, T. Xue, K. Goda, and H. He, "Direct control of store-operated calcium channels by ultrafast laser", Cell Research (2021)

flag flag flag

Card image cap
Hydrodynamic particle focusing

T. Zhang, M. Namoto, .., Y. Yalikun, M. Li, Y. Hosokawa, "Hydrodynamic particle focusing enhanced by femtosecond laser deep grooving at low Reynolds numbers", Scientific Reports (2021)

flag flag

Card image cap
Cell rotation

T. Tang, Y. Hosokawa, T. Hayakawa, Y. Tanaka, W. Li, M. Li, and Y. Yalikun, "Rotation of biological cells: fundamentals and applications", Engineering (2021)


flag flag

Card image cap
Efficient coherent Raman

R. Kameyama, S. Takizawa, K. Hiramatsu, and K. Goda, "Dual-comb coherent Raman spectroscopy with near 100% duty clcle", ACS Photonics (2020)


flag flag flag

Card image cap
Metal-free SERS

N. Chen, T. Xiao, Z. Luo, Y. Kitahama, N. Kishimoto, T. Ito, Z. Cheng, and K. Goda, "Porous carbon nanowire array for surface-enhanced Raman spectroscopy", Nature Communications (2020)

flag flag flag

Card image cap
Yeast screening by shape

P. Liu, H. Liu, D. Yuan, D. Jang, S. Yan, and M. Li, "Separation and enrichment of yeast Saccharomyces cerevisiae by shape using viscoelastic microfluidics", Analytical Chemistry (2020)


flag flag flag

Card image cap
Raman image-based cell sorting

N. Nitta, T. Iino, A. Isozaki, M. Yamagishi, Y. Kitahama, S. Sakuma, .., and K. Goda, "Raman image-activated cell sorting", Nature Communications (2020)


flag flag flag

Card image cap
AI on a chip

A. Isozaki, J. Harmon, Y. Zhou, S. Li, Y. Nakagawa, M. Hayashi, H. Mikami, C. Lei, and K. Goda, "AI on a chip", Lab on a Chip (2020)



flag flag flag

Card image cap
Time-stretch imaging

Y. Weng, L. Mei, G. Wu, S. Chen, B. Zhan, K. Goda, S. Liu, and C. Lei, "Analysis of signal detection configurations in optical time-stretch imaging", Optics Express (2020)


flag flag flag

Card image cap
Mechanical properties of cells

Y. Hao, S. Cheng, Y. Tanaka, Y. Hosokawa, Y. Yalikun, and M. Li, "Mechanical properties of single cells: Measurement methods and applications", Biotechnology Advances (2020)

flag flag

Card image cap
Dielectrophoretic array sorting

A. Isozaki, Y. Nakagawa, .., D. Di Carlo, and K. Goda, "Sequentially addressable dielectrophoretic array for high-throughput sorting of large-volume biological compartments", Science Advances (2020)

flag flag flag

Card image cap
Image-activated cell sorting 2.0

A. Isozaki, H. Mikami, H. Tezuka, H. Matsumura, K. Huang, .., T. Sugimura, N. Nitta, and K. Goda, "Intelligent image-activated cell sorting 2.0", Lab on a Chip (2020)


flag flag flag flag flag

Card image cap
Virtual-freezing imaging

H. Mikami, M. Kawaguchi, C.-J. Huang, H. Matsumura, .., S. Matsusaka, C.-W. Sun, Y. Ozeki, and K. Goda, "Virtual-freezing fluorescence imaging flow cytometry", Nature Communications (2020)

flag flag flag flag

Card image cap
Platelet aggregate classification

Y. Zhou, A. Yasumoto, C. Lei, C.-J. Huang, H. Kobayashi, Y. Wu, S. Yan, C.-W. Sun, Y. Yatomi, and K. Goda, "Intelligent classification of platelet aggregates by agonist type", eLife (2020)

flag flag flag flag

Card image cap
Virtual time-stretch imaging

H. Yan, Y. Wu, Y. Zhou, M. Xu, P. Paie, C. Lei, S. Yan, and K. Goda, "Virtual optofluidic time-stretch quantitative phase imaging", APL Photonics (2020)



flag flag flag

Card image cap
Spatiotemporal cell monitoring

Y. Yonamine, K. Hiramatsu, .., and Y. Hoshino, "Spatiotemporal monitoring of intracellular metabolic dynamics by resonance Raman microscopy with stable isotope labeling", RSC Advances (2020)

flag flag flag

Card image cap
Large-scale single-cell analysis

K. Hiramatsu, .., and K. Goda, "Large-scale label-free single-cell analysis of paramylon in Euglena gracilis by high-throughput broadband Raman flow cytometry", Biomedical Optics Express (2020)

flag flag flag

Card image cap
Ultrafast single-pixel imaging

H. Kanno, H. Mikami, and K. Goda, "High-speed single-pixel imaging by frequency-time-division multiplexing", Optics Letters (2020)



flag flag flag

Card image cap
Temporally interleaved imaging

Y. Weng, G. Wu, L. Mei, Q. Wang, K. Goda, S. Liu, and C. Lei, "Temporally interleaved optical time-stretch imaging", Optics Letters (2020)



flag flag flag

Card image cap
Glass microfluidics

Y. Yalikun, O. Nobutoshi, D. Ma, and Y. Tanaka, "Horizontal connection method for glass microfluidic devices", Micro & Nano Letters (2020)



flag

Card image cap
Compressed coherent Raman

S. Takizawa, K. Hiramatsu, and K. Goda, "Compressed time-domain coherent Raman spectroscopy with real-time random sampling", Vibrational Spectroscopy (2020)


flag flag flag

Card image cap
Accurate cell classification

J. Harmon, H. Mikami, .., and K. Goda, "High-speed accurate classification of microalgae by intelligent frequency-division-multiplexed fluorescence imaging flow cytometry", OSA Continuum (2020)

flag flag flag

Card image cap
Quantitative phase imaging

Y. Wu, Y. Zhou, C.-J. Huang, H. Kobayashi, S. Yan, .., Y. Yatomi, C. Lei, and K. Goda, "Intelligent frequency-shifted optofluidic time-stretch quantitative phase imaging", Optics Express (2020)

flag flag flag flag

Card image cap
Microfluidic chip deformation

Y. Yalikun, N. Ota, B. Guo, T. Tang, C. Lei, .., D. Di Carlo, K. Goda, and Y. Tanaka, "Effects of flow-induced microfluidic chip wall deformation on imaging flow cytometry", Cytometry Part A (2019)

flag flag flag flag

Card image cap
Ultrafast fluoRaman spectroscopy

M. Lindley, K. Hiramatsu, H. Nomoto, F. Shibata, T. Takeshita, S. Kawano, and K. Goda, "Ultrafast simultaneous Raman-fluorescence spectroscopy", Analytical Chemistry (2019)


flag flag flag

Card image cap
Focusing of submicron particles

T. Zhang, Z.-Y. Hong, S.-Y. Tang, W. Li, D. W. Inglis, Y. Hosokawa, Y. Yalikun, and M. Li, "Focusing of sub-micrometer particles in microfluidic devices", Lab on a Chip (2019)


flag flag

Card image cap
Low-frequency Raman

W. Peterson, K. Hiramatsu, and K. Goda, "Sagnac-enhanced impulsive stimulated Raman scattering for highly sensitive low-frequency Raman spectroscopy", Optics Letters (2019)


flag flag flag

Card image cap
Ultrafast particle isolation

T. Iino, K. Okano, .., K. Goda, and Y. Hosokawa, "High-speed microparticle isolation unlimited by Poisson statistics", Lab on a Chip (2019)



flag flag

Card image cap
Sheathless separation of microbes

D. Yuan, Q. Zhao, S. Yan, .., M. Li, and W. Li, "Sheathless separation of microalgae from bacteria using a simple straight channel based on viscoelastic microfluidics", Lab on a Chip (2019)

flag flag

Card image cap
Intelligent chemosensitivity testing

H. Kobayashi, C. Lei, .., Y. Yatomi, and K. Goda, "Intelligent whole-blood imaging flow cytometry for simple, rapid, and cost-effective drug-susceptibility testing of leukemia", Lab on a Chip (2019)

flag flag flag flag flag flag

Card image cap
A practical guide to IACS

A. Isozaki, H. Mikami, K. Hiramatsu, S. Sakuma, Y. Kasai, .., T. Sugimura, Y. Ozeki, N. Nitta, and K. Goda, "A practical guide to intelligent image-activated cell sorting", Nature Protocols (2019)

flag flag

Card image cap
Intelligent image de-blurring

F. Zhang, C. Lei, C.-J. Huang, H. Kobayashi, C.-W. Sun, and K. Goda, "Intelligent image de-blurring for imaging flow cytometry", Cytometry Part A (2019)


flag flag